News

June, 2026

Three papers accepted at Journal of American College of Cardiology, Science Translational Medicine, and Journal of Clinical Investigation!

May, 2026

Three new preprints from the lab! One led by Shengxin introducing a novel framework to benchmark the individual-level clinical readiness of PRS for coronary artery disease (Liang, Kim et al., medRxiv), one led by Linke developing a ML approach for cross-platform proteomic imputation to address SomaScan–Olink discordance that has hindered replication of protein–disease associations (Li, Alaa et al., bioRxiv), and one co-led by Zhi reporting the largest CHIP GWAS and PheWAS to date (N>1 million) (Uddin, Yu et al., medRxiv).

May, 2026

Our paper co-led by Linke establishing link between CHIP and inflammatory bowel disease — and that the oral drug APX3330 can modify it — is now published in Blood (Kumar, Li et al.), with an accompanying podcast and review article.

May, 2026

Three papers accepted at JAMA Cardiology, Cell Genomics, and Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB)!

May, 2026

Welcome Yushu to the group!

April, 2026

Congrats to Linke, Xinyu, Shengxin, Kathy, and Anthea on accepting their PhD offers! They are heading to Harvard University (x2: Statistical Genetics & Genetic Epidemiology, Cancer Epidemiology), University of Cambridge, and Duke University (x2: Computational Biology & Bioinformatics, Genetics & Genomics)!

April, 2026

Four papers we (Linke and Zhi) contributed to were accepted by the European Heart Journal, Cardiovascular Research, Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB), and Clinical and Experimental Rheumatology!

March, 2026

Congrats to Meghana on matching to Massachusetts General Hospital Internal Medicine for residency!

Feb, 2026

Welcome Qiayi to the group!

Jan, 2026

Three papers we (Linke and Zhi) led/supervised or contributed to were accepted by Nature Genetics, Blood, and Nature Communications!

November, 2025

Welcome Linda and Christina to the group!

October, 2025

Welcome Antony and Yuan to the group!

October, 2025

Welcome Cyril and Wenxin to the group!

September, 2025

Zhi got elected Fellow of the American Heart Association (FAHA) by the Council on Genomic and Precision Medicine!

August, 2025

Xinyu’s ASHG abstract selected as Reviewers’ Choice Abstract!

July, 2025

Four abstracts led by Linke (CHIP transcriptomics), Xinyu (CHIP modifiers), Vanessa (PRS scoring in clinics), and Anthea (genetic basis of cardiac radiomic features) were accepted to the 2025 ASHG Annual Meeting; Linke’s was selected for an oral presentation and Xinyu’s for a lightning talk!

July, 2025

Zhi will serve on the ASHG Program Committee for three years starting January 1, 2026!

July, 2025

Three papers we (Kathy and Zhi) contributed to were published in Nature, Circulation, and JACC: Advances!

July, 2025

Welcome Alaina to the group!

May, 2025

Zhi got Early Career Achievement award from CHARGE!

April, 2025

Three papers on clonal hematopoiesis and kidney diseases published on the April issue of Journal of the American Society of Nephrology!

January, 2025

Welcome Vanessa and Yiru to the group!

December, 2024

Welcome Linke to the lab!

November 14, 2024

Welcome Xinyu, Kathy, and Anthea to the group!

August 30, 2024

Our paper is out in European Heart Journal! We used murine and human genetic studies to infer that individuals with TET2 clonal hematopoiesis may derive potent cardiovascular risk reduction with colchicine.

August 21, 2024

Our preprint led by super-talented Meghana is out! We combined deep learning, prediction modeling, and GWAS to uncover the shared genetic basis between spleen and coronary artery disease.